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NMR Structure in a Membrane Environment Reveals Putative Amyloidogenic Regions of the SEVI Precursor Peptide PAP(248–286)

Semen is the main vector for HIV transmission worldwide. Recently, a peptide fragment (PAP(248–286)) has been isolated from seminal fluid that dramatically enhances HIV infectivity by up to four to five orders of magnitude. PAP(248–286) appears to enhance HIV infection by forming amyloid fibers know...

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Detalhes bibliográficos
Main Authors: Nanga, Ravi P., Brender, Jeffrey R., Vivekanandan, Subramanian, Popovych, Nataliya, Ramamoorthy, Ayyalusamy
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792124/
https://ncbi.nlm.nih.gov/pubmed/19995078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908170s
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