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High Titer HIV-1 V3-Specific Antibodies with Broad Reactivity but Low Neutralizing Potency in Acute Infection and Following Vaccination

Identifying the earliest neutralizing antibody specificities that are elicited following infection or vaccination by HIV-1 is an important objective of current HIV/AIDS vaccine research. We have shown previously that transplantation of HIV-1 V3 epitopes into an HIV-2 envelope (Env) scaffold provides...

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書誌詳細
主要な著者: Davis, Katie L., Gray, Elin S., Moore, Penny L., Decker, Julie M., Salomon, Aidy, Montefiori, David C., Graham, Barney S., Keefer, Michael C., Pinter, Abraham, Morris, Lynn, Hahn, Beatrice H., Shaw, George M.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792036/
https://ncbi.nlm.nih.gov/pubmed/19298995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.02.022
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