The anti-apoptotic protein HAX-1 is a regulator of cardiac function

The HS-1 associated protein X-1 (HAX-1) is a ubiquitously expressed protein that protects cardiomyocytes from programmed cell death. Here we identify HAX-1 as a regulator of contractility and calcium cycling in the heart. HAX-1 overexpression reduced sarcoplasmic reticulum Ca-ATPase (SERCA2) pump ac...

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Bibliografiske detaljer
Main Authors: Zhao, Wen, Waggoner, Jason R., Zhang, Zhi-Guo, Lam, Chi Keung, Han, Peidong, Qian, Jiang, Schroder, Paul M., Mitton, Bryan, Kontrogianni-Konstantopoulos, Aikaterini, Robia, Seth L., Kranias, Evangelia G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791603/
https://ncbi.nlm.nih.gov/pubmed/19920172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906998106
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