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HAX-1 regulates cyclophilin-D levels and mitochondria permeability transition pore in the heart

The major underpinning of massive cell death associated with myocardial infarction involves opening of the mitochondrial permeability transition pore (mPTP), resulting in disruption of mitochondria membrane integrity and programmed necrosis. Studies in human lymphocytes suggested that the hematopoie...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lam, Chi Keung, Zhao, Wen, Liu, Guan-Sheng, Cai, Wen-Feng, Gardner, George, Adly, George, Kranias, Evangelia G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664353/
https://ncbi.nlm.nih.gov/pubmed/26553996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1508760112
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