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Use of high throughput sequencing to observe genome dynamics at a single cell level
With the development of high throughput sequencing technology, it becomes possible to directly analyze mutation distribution in a genome-wide fashion, dissociating mutation rate measurements from the traditional underlying assumptions. Here, we sequenced several genomes of Escherichia coli from colo...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791585/ https://ncbi.nlm.nih.gov/pubmed/19934054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906681106 |
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