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Distinct Functions of Vascular Endothelial and Smooth Muscle PPARγ in Regulation of Blood Pressure and Vascular Tone
Thiazolidinediones (TZDs) are peroxisome proliferators–activated receptor gamma (PPARγ) activators that exhibit antihypertensive and vasculoprotective effects. Here we describe the use of Tie2Cre/flox and SM22Cre/flox mice, which respectively lacked PPARγ in the endothelium and the smooth muscle, to...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791342/ https://ncbi.nlm.nih.gov/pubmed/19075043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623308328545 |
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