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Distinct Functions of Vascular Endothelial and Smooth Muscle PPARγ in Regulation of Blood Pressure and Vascular Tone

Thiazolidinediones (TZDs) are peroxisome proliferators–activated receptor gamma (PPARγ) activators that exhibit antihypertensive and vasculoprotective effects. Here we describe the use of Tie2Cre/flox and SM22Cre/flox mice, which respectively lacked PPARγ in the endothelium and the smooth muscle, to...

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Autors principals: Wang, Ningning, Symons, J. David, Zhang, Hui, Jia, Zhanjun, Gonzalez, Frank J., Yang, Tianxin
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791342/
https://ncbi.nlm.nih.gov/pubmed/19075043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623308328545
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