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KLF4-dependent, PPARγ-induced expression of GPA33 in colon cancer cell lines

The glycoprotein A33 (GPA33) is a colon cancer antigen. Phase I trials with (131)I and (125)I monoclonal antibody A33 in colon carcinoma patients showed excellent localization to colorectal cancer and some evidence of tumor response. Using DNA microarrays, we have identified the GPA33 gene as a targ...

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Detalhes bibliográficos
Main Authors: Rageul, Julie, Mottier, Stéphanie, Jarry, Anne, Shah, Yatrik, Théoleyre, Sandrine, Masson, Damien, Gonzalez, Frank J., Laboisse, Christian L., Denis, Marc G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791338/
https://ncbi.nlm.nih.gov/pubmed/19551868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24683
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