Mucosal IL-10 and TGF-β play crucial roles in preventing LPS-driven, IFN-γ–mediated epithelial damage in human colon explants

IL-10 is an immunomodulatory cytokine that plays an obligate role in preventing spontaneous enterocolitis in mice. However, little is known about IL-10 function in the human intestinal mucosa. We showed here that IL-10 was constitutively expressed and secreted by the human normal colonic mucosa, inc...

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Detaylı Bibliyografya
Asıl Yazarlar: Jarry, Anne, Bossard, Céline, Bou-Hanna, Chantal, Masson, Damien, Espaze, Eric, Denis, Marc G., Laboisse, Christian L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2008
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230656/
https://ncbi.nlm.nih.gov/pubmed/18259614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32140
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