Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon

ISG15 (ISG15 ubiquitin-like modifier), a ubiquitin-like protein, is one of the major type I IFN (interferon) effector systems. ISG15 can be conjugated to target proteins (ISGylation) via the stepwise action of E1, E2, and E3 enzymes. Conjugated ISG15 can be removed (deISGylated) from target proteins...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Xu, Daichao, Zhang, Tao, Xiao, Juan, Zhu, Kezhou, Wei, Ran, Wu, Zheming, Meng, Huyan, Li, Ying, Yuan, Junying
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502663/
https://ncbi.nlm.nih.gov/pubmed/25906440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1023982
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