Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1

Interferons (IFNs) induce the expression of interferon-stimulated genes (ISGs) for defense against numerous viral infections, including classical swine fever virus (CSFV). However, the mechanisms underlying the effect of ISGs on CSFV infection are rarely reported. In this study, we demonstrate that...

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Detalhes bibliográficos
Publicado no:Vet Res
Main Authors: Li, Cheng, Wang, Yifan, Zheng, Hongqing, Dong, Wang, Lv, Huifang, Lin, Jihui, Guo, Kangkang, Zhang, Yanming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038623/
https://ncbi.nlm.nih.gov/pubmed/32093773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-020-00753-5
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