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Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1

Interferons (IFNs) induce the expression of interferon-stimulated genes (ISGs) for defense against numerous viral infections, including classical swine fever virus (CSFV). However, the mechanisms underlying the effect of ISGs on CSFV infection are rarely reported. In this study, we demonstrate that...

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Библиографические подробности
Опубликовано в: :Vet Res
Главные авторы: Li, Cheng, Wang, Yifan, Zheng, Hongqing, Dong, Wang, Lv, Huifang, Lin, Jihui, Guo, Kangkang, Zhang, Yanming
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038623/
https://ncbi.nlm.nih.gov/pubmed/32093773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-020-00753-5
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