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Bone loss in survival motor neuron (Smn(−/−)SMN2) genetic mouse model of spinal muscular atrophy
Spinal muscular atrophy (SMA) is characterized by degenerating lower motor neurons and an increased incidence of congenital bone fractures. Survival motor neuron (SMN) levels are significantly reduced due to deletions/mutations in the telomeric SMN1 gene in these patients. We utilized the Smn(−/−) S...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2791336/ https://ncbi.nlm.nih.gov/pubmed/19434631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2566 |
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