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A Strategy for Adenovirus Vector Targeting with a Secreted Single Chain Antibody

BACKGROUND: Successful gene therapy will require targeted delivery vectors capable of self-directed localization. In this regard, the use of antibodies or single chain antibody fragments (scFv) in conjunction with adenovirus (Ad) vectors remains an attractive means to achieve cell-specific targeting...

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Bibliografiske detaljer
Main Authors: Glasgow, Joel N., Mikheeva, Galina, Krasnykh, Victor, Curiel, David T.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791226/
https://ncbi.nlm.nih.gov/pubmed/20027223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008355
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