Heparan Sulfate Phage Display Antibodies Identify Distinct Epitopes with Complex Binding Characteristics: INSIGHTS INTO PROTEIN BINDING SPECIFICITIES

Heparan sulfate (HS) binds and modulates the transport and activity of a large repertoire of regulatory proteins. The HS phage display antibodies are powerful tools for the analysis of native HS structure in situ; however, their epitopes are not well defined. Analysis of the binding specificities of...

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Autors principals: Thompson, Sophie M., Fernig, David G., Jesudason, Edwin C., Losty, Paul D., van de Westerlo, Els M. A., van Kuppevelt, Toin H., Turnbull, Jeremy E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Glycobiology and Extracellular Matrices
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790993/
https://ncbi.nlm.nih.gov/pubmed/19837661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.009712
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