The Hsp90 Inhibitor Geldanamycin Abrogates Colocalization of eIF4E and eIF4E-Transporter into Stress Granules and Association of eIF4E with eIF4G

The eukaryotic translation initiation factor eIF4E plays a critical role in the control of translation initiation through binding to the mRNA 5′ cap structure. eIF4E is also a component of processing bodies and stress granules, which are two types of cytoplasmic RNA granule in which translationally...

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Main Authors: Suzuki, Yukari, Minami, Michiko, Suzuki, Miho, Abe, Keiko, Zenno, Shuhei, Tsujimoto, Masafumi, Matsumoto, Ken, Minami, Yasufumi
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
主題:
Protein Synthesis, Post-Translational Modification, and Degradation
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790990/
https://ncbi.nlm.nih.gov/pubmed/19850929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.036285
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