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A Common Mutation in Paraoxonase-2 Results in Impaired Lactonase Activity

Paraoxonases (PONs) are a family of lactonases with promiscuous enzyme activity that has been implicated in multiple diseases. PON2 is intracellularly located, is the most ubiquitously expressed PON, and has the highest lactonase activity of the PON family members. Whereas some single-nucleotide pol...

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Bibliographische Detailangaben
Hauptverfasser: Stoltz, David A., Ozer, Egon A., Recker, Thomas J., Estin, Miriam, Yang, Xia, Shih, Diana M., Lusis, Aldons J., Zabner, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790986/
https://ncbi.nlm.nih.gov/pubmed/19840942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.051706
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