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A Common Mutation in Paraoxonase-2 Results in Impaired Lactonase Activity

Paraoxonases (PONs) are a family of lactonases with promiscuous enzyme activity that has been implicated in multiple diseases. PON2 is intracellularly located, is the most ubiquitously expressed PON, and has the highest lactonase activity of the PON family members. Whereas some single-nucleotide pol...

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Detalhes bibliográficos
Main Authors: Stoltz, David A., Ozer, Egon A., Recker, Thomas J., Estin, Miriam, Yang, Xia, Shih, Diana M., Lusis, Aldons J., Zabner, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790986/
https://ncbi.nlm.nih.gov/pubmed/19840942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.051706
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