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Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1

Pseudomonas aeruginosa uses quorum sensing, an interbacterial communication system, to regulate gene expression. The signaling molecule N-3-oxododecanoyl homoserine lactone (3OC12-HSL) is thought to play a central role in quorum sensing. Since 3OC12-HSL can be degraded by paraoxonase (PON) family me...

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Detalhes bibliográficos
Main Authors: Stoltz, David A., Ozer, Egon A., Taft, Peter J., Barry, Marilyn, Liu, Lei, Kiss, Peter J., Moninger, Thomas O., Parsek, Matthew R., Zabner, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515384/
https://ncbi.nlm.nih.gov/pubmed/18704198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35147
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