N-terminal Domains Elicit Formation of Functional Pmel17 Amyloid Fibrils

Pmel17 is a transmembrane protein that mediates the early steps in the formation of melanosomes, the subcellular organelles of melanocytes in which melanin pigments are synthesized and stored. In melanosome precursor organelles, proteolytic fragments of Pmel17 form insoluble, amyloid-like fibrils up...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Watt, Brenda, van Niel, Guillaume, Fowler, Douglas M., Hurbain, Ilse, Luk, Kelvin C., Stayrook, Steven E., Lemmon, Mark A., Raposo, Graça, Shorter, James, Kelly, Jeffery W., Marks, Michael S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Protein Structure and Folding
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790984/
https://ncbi.nlm.nih.gov/pubmed/19840945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.047449
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