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Smad3 Differentially Regulates the Induction of Regulatory and Inflammatory T Cell Differentiation
Transforming growth factor β (TGF-β) is a crucial cytokine with pleiotropic functions on immune cells. In CD4(+) T cells, TGF-β is required for induction of both regulatory T and Th17 cells. However, the molecular mechanism underlying this differential T cell fate decision remains unclear. In this s...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790957/ https://ncbi.nlm.nih.gov/pubmed/19887374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.078238 |
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