The HSV-1 ICP27 RGG box specifically binds flexible, GC-rich sequences but not G-quartet structures

Eitemau Tebyg

• Three Arginine Residues within the RGG Box Are Crucial for ICP27 Binding to Herpes Simplex Virus 1 GC-Rich Sequences and for Efficient Viral RNA Export
  gan: Corbin-Lickfett, Kara A., et al.
  Cyhoeddwyd: (2010)
• Arginine Methylation of the ICP27 RGG Box Regulates ICP27 Export and Is Required for Efficient Herpes Simplex Virus 1 Replication
  gan: Souki, Stuart K., et al.
  Cyhoeddwyd: (2009)
• Arginine Methylation of the ICP27 RGG Box Regulates the Functional Interactions of ICP27 with SRPK1 and Aly/REF during Herpes Simplex Virus 1 Infection
  gan: Souki, Stuart K., et al.
  Cyhoeddwyd: (2009)
• ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif
  gan: Sandri-Goldin, Rozanne M.
  Cyhoeddwyd: (1998)
• Arginine Methylation of the RGG Box Does Not Appear To Regulate ICP27 Import during Herpes Simplex Virus Infection
  gan: Souki, Stuart K., et al.
  Cyhoeddwyd: (2011)