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The HSV-1 ICP27 RGG box specifically binds flexible, GC-rich sequences but not G-quartet structures
Herpes simplex virus 1 (HSV-1) protein ICP27, an important regulator for viral gene expression, directly recognizes and exports viral RNA through an N-terminal RGG box RNA binding motif, which is necessary and sufficient for RNA binding. An ICP27 N-terminal peptide, including the RGG box RNA binding...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790906/ https://ncbi.nlm.nih.gov/pubmed/19783816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp793 |
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