The HSV-1 ICP27 RGG box specifically binds flexible, GC-rich sequences but not G-quartet structures

Herpes simplex virus 1 (HSV-1) protein ICP27, an important regulator for viral gene expression, directly recognizes and exports viral RNA through an N-terminal RGG box RNA binding motif, which is necessary and sufficient for RNA binding. An ICP27 N-terminal peptide, including the RGG box RNA binding...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Corbin-Lickfett, Kara A., Chen, I-Hsiung Brandon, Cocco, Melanie J., Sandri-Goldin, Rozanne M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2009
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790906/
https://ncbi.nlm.nih.gov/pubmed/19783816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp793
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky