Revisiting the planarity of nucleic acid bases: Pyramidilization at glycosidic nitrogen in purine bases is modulated by orientation of glycosidic torsion

We describe a novel, fundamental property of nucleobase structure, namely, pyramidilization at the N1/9 sites of purine and pyrimidine bases. Through a combined analyses of ultra-high-resolution X-ray structures of both oligonucleotides extracted from the Nucleic Acid Database and isolated nucleotid...

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Main Authors: Sychrovsky, Vladimir, Foldynova-Trantirkova, Silvie, Spackova, Nada, Robeyns, Koen, Van Meervelt, Luc, Blankenfeldt, Wulf, Vokacova, Zuzana, Sponer, Jiri, Trantirek, Lukas
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790901/
https://ncbi.nlm.nih.gov/pubmed/19786496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp783
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