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IRF4: Immunity. Malignancy! Therapy?

IRF4, a member of the IRF family of transcription factors, is expressed in cells of the immune system where it transduces signals from various receptors to activate or repress gene expression. IRF4 expression is a key regulator of several steps in lymphoid, myeloid and dendritic cell differentiation...

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Bibliographic Details
Main Authors: Shaffer, Arthur L., Tolga Emre, N. C., Romesser, Paul B., Staudt, Louis M.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790720/
https://ncbi.nlm.nih.gov/pubmed/19383829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1845
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