Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition

We have identified oleuropein (Ole) and hydroxytyrosol (HT) as a unique class of HIV-1 inhibitors from olive leaf extracts effective against viral fusion and integration. We used molecular docking simulation to study the interactions of Ole and HT with viral targets. We find that Ole and HT bind to...

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Detaylı Bibliyografya
Asıl Yazarlar: Lee-Huang, Sylvia, Huang, Philip Lin, Zhang, Dawei, Lee, Jae Wook, Bao, Ju, Sun, Yongtao, Chang, Young-Tae, Zhang, John, Huang, Paul Lee
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Inc. 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790717/
https://ncbi.nlm.nih.gov/pubmed/17275783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.01.071
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