Ribonuclease A variants with potent cytotoxic activity

Select members of the bovine pancreatic ribonuclease A (RNase A) superfamily are potent cytotoxins. These cytotoxic ribonucleases enter the cytosol, where they degrade cellular RNA and cause cell death. Ribonuclease inhibitor (RI), a cytosolic protein, binds to members of the RNase A superfamily wit...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Leland, Peter A., Schultz, L. Wayne, Kim, Byung-Moon, Raines, Ronald T.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1998
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9724716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.18.10407
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