Okazaki fragment processing: Modulation of the strand displacement activity of DNA polymerase δ by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1

DNA polymerase (pol) δ is essential for both leading and lagging strand DNA synthesis during chromosomal replication in eukaryotes. Pol δ has been implicated in the Okazaki fragment maturation process for the extension of the newly synthesized fragment and for the displacement of the RNA/DNA segment...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Maga, Giovanni, Villani, Giuseppe, Tillement, Vanessa, Stucki, Manuel, Locatelli, Giada A., Frouin, Isabelle, Spadari, Silvio, Hübscher, Ulrich
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64676/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11724925/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251193198
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