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The TREX2 3′→ 5′ Exonuclease Physically Interacts with DNA Polymerase δ and Increases Its Accuracy

Proofreading function by the 3′→ 5′ exonuclease of DNA polymerase δ (pol δ) is consistent with the observation that deficiency of the associated exonuclease can lead to a strong mutation phenotype, high error rates during DNA replication, and ultimately cancer. We have isolated pol δd from isotonic...

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Principais autores: Igor V. Shevelev, Kristijan Ramadan, Ulrich Hubscher
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2002-01-01
Series:The Scientific World Journal
Acceso en liña:http://dx.doi.org/10.1100/tsw.2002.99
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