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Mitogen-Activated Protein Kinases Mediate Upregulation of Hypothalamic AT(1) Receptors in Heart Failure Rats

In heart failure (HF), angiotensin type-1 receptor (AT(1)-R) expression is upregulated in brain regions regulating sympathetic drive, blood pressure and body fluid homeostasis. However, the mechanism by which brain AT(1)-R are upregulated in HF remains unknown. The present study examined the hypothe...

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Bibliographic Details
Main Authors: Wei, Shun-Guang, Yu, Yang, Zhang, Zhi-Hua, Weiss, Robert M., Felder, Robert B.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790407/
https://ncbi.nlm.nih.gov/pubmed/18768402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.108.113639
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