Does Aldosterone Upregulate the Brain Renin-Angiotensin System in Rats with Heart Failure?

The brain renin-angiotensin system (RAS) contributes to increased sympathetic drive in heart failure (HF). The factors upregulating the brain RAS in HF remain unknown. We hypothesized that aldosterone (ALDO), a downstream product of the systemic RAS that crosses the blood-brain barrier, signals the...

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Bibliographic Details
Main Authors: Yu, Yang, Wei, Shun-Guang, Zhang, Zhi-Hua, Gomez-Sanchez, Elise, Weiss, Robert M, Felder, Robert B
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790402/
https://ncbi.nlm.nih.gov/pubmed/18227408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.107.099796
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