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Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis
Macrophages exhibit endoplasmic reticulum (ER) stress when exposed to lipotoxic signals associated with atherosclerosis, although the pathophysiological significance and the underlying mechanisms remain unknown. Here, we demonstrate that mitigation of ER stress with a chemical chaperone results in m...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790330/ https://ncbi.nlm.nih.gov/pubmed/19966778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2067 |
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