Tilting the balance between facilitatory and inhibitory functions of mammalian and Drosophila Complexins orchestrates synaptic vesicle exocytosis

SNARE-mediated synaptic exocytosis is orchestrated by facilitatory and inhibitory mechanisms. Genetic ablations of Complexins, a family of SNARE complex–binding proteins, in mice and Drosophila cause apparently opposite effects on neurotransmitter release, leading to contradictory hypotheses of Comp...

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Detalhes bibliográficos
Main Authors: Xue, Mingshan, Lin, Yong Qi, Pan, Hongling, Reim, Kerstin, Deng, Hui, Bellen, Hugo J., Rosenmund, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790209/
https://ncbi.nlm.nih.gov/pubmed/19914185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.09.043
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