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Amyloid-β Dynamics are Regulated by Orexin and the Sleep-Wake Cycle
Amyloid-β (Aβ) accumulation in the brain extracellular space is a hallmark of Alzheimer’s disease (AD). The factors regulating this process are only partly understood. Aβ aggregation is a concentration-dependent process that is likely to be dependent on changes in brain interstitial fluid (ISF) leve...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789838/ https://ncbi.nlm.nih.gov/pubmed/19779148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1180962 |
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