Amyloid-β Dynamics are Regulated by Orexin and the Sleep-Wake Cycle

Amyloid-β (Aβ) accumulation in the brain extracellular space is a hallmark of Alzheimer’s disease (AD). The factors regulating this process are only partly understood. Aβ aggregation is a concentration-dependent process that is likely to be dependent on changes in brain interstitial fluid (ISF) leve...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Kang, Jae-Eun, Lim, Miranda M., Bateman, Randall J., Lee, James J., Smyth, Liam P., Cirrito, John R., Fujiki, Nobuhiro, Nishino, Seiji, Holtzman, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789838/
https://ncbi.nlm.nih.gov/pubmed/19779148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1180962
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi