Discoidin Domain Receptor-1 Deficiency Attenuates Atherosclerotic Calcification and Smooth Muscle Cell-Mediated Mineralization

Intimal calcification is a feature of advanced atherosclerotic disease that predicts a two- to eightfold increase in the risk of coronary events. Type I collagen promotes vascular smooth muscle cell-mediated calcification, although the mechanism by which this occurs is unknown. The discoidin domain...

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Bibliographic Details
Main Authors: Ahmad, Pamela J., Trcka, Daniel, Xue, Siming, Franco, Christopher, Speer, Mei Y., Giachelli, Cecilia M., Bendeck, Michelle P.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789613/
https://ncbi.nlm.nih.gov/pubmed/19893047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080734
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