End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa

A phospholipase C/ sphingomyelinase from Pseudomonas aeruginosa has been assayed on vesicles containing phosphatidylcholine, sphingomyelin, phosphatidylethanolamine and cholesterol, at equimolar ratios. The enzyme activity modifies the bilayer chemical composition giving rise to diacylglycerol (DAG)...

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Bibliographic Details
Main Authors: Ibarguren, Maitane, Bomans, Paul H. H., Frederik, Peter M., Stonehouse, Martin, Vasil, Michael L., Alonso, Alicia, Goñi, Félix M.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789492/
https://ncbi.nlm.nih.gov/pubmed/19891956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.10.017
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