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Imaging the early stages of phospholipase C/sphingomyelinase activity on vesicles containing coexisting ordered-disordered and gel-fluid domains

The binding and early stages of activity of a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa on giant unilamellar vesicles (GUV) have been monitored using fluorescence confocal microscopy. Both the lipids and the enzyme were labeled with specific fluorescent markers. GUV consisted of a...

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Detalhes bibliográficos
Main Authors: Ibarguren, Maitane, López, David J., Montes, L.-Ruth, Sot, Jesús, Vasil, Adriana I., Vasil, Michael L., Goñi, Félix M., Alonso, Alicia
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284157/
https://ncbi.nlm.nih.gov/pubmed/21252263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M012591
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