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Decreased Neurokinin-1 (Substance P) Receptor Binding in Patients with Panic Disorder: Positron Emission Tomographic Study with [(18)F]SPA-RQ

BACKGROUND: Positron emission tomography (PET) can localize and quantify neurokinin-1 (NK(1)) receptors in brain using the nonpeptide antagonist radioligand, [(18)F]SPA-RQ. We sought to determine if patients with panic disorder have altered density of NK(1) receptors in brain because of their histor...

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Detalhes bibliográficos
Main Authors: Fujimura, Yota, Yasuno, Fumihiko, Farris, Amanda, Liow, Jeih-San, Geraci, Marilla, Drevets, Wayne, Pine, Daniel S., Ghose, Subroto, Lerner, Alicja, Hargreaves, Richard, Burns, H. Donald, Morse, Cheryl, Pike, Victor W., Innis, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789441/
https://ncbi.nlm.nih.gov/pubmed/19200949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.12.027
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