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TLR3-Stimulated Dendritic Cells Up-regulate B7-H1 Expression and Influence the Magnitude of CD8 T Cell Responses to Tumor Vaccination

Agonists of TLR have been explored as vaccine adjuvants for tumor immunotherapy. However, their immunological consequences are not fully understood. Although TLR signaling increases the functional potential of dendritic cells (DCs) for priming T cells, coinduction of potentially negative immunoregul...

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Detalhes bibliográficos
Main Authors: Pulko, Vesna, Liu, Xin, Krco, Christopher J., Harris, Kimberley J., Frigola, Xavier, Kwon, Eugene D., Dong, Haidong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789393/
https://ncbi.nlm.nih.gov/pubmed/19710456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900974
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