TLR3-Stimulated Dendritic Cells Up-regulate B7-H1 Expression and Influence the Magnitude of CD8 T Cell Responses to Tumor Vaccination

Agonists of TLR have been explored as vaccine adjuvants for tumor immunotherapy. However, their immunological consequences are not fully understood. Although TLR signaling increases the functional potential of dendritic cells (DCs) for priming T cells, coinduction of potentially negative immunoregul...

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Bibliographic Details
Main Authors: Pulko, Vesna, Liu, Xin, Krco, Christopher J., Harris, Kimberley J., Frigola, Xavier, Kwon, Eugene D., Dong, Haidong
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789393/
https://ncbi.nlm.nih.gov/pubmed/19710456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900974
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