Lack of Evidence for Green Tea Polyphenols as DNA Methylation Inhibitors in Murine Prostate

Green tea polyphenols (GTPs) have been reported to inhibit DNA methylation in cultured cells. Here we tested whether oral consumption of GTPs affects normal or cancer specific DNA methylation in vivo, using mice. Wildtype (WT) and Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) mice were adminis...

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Detalhes bibliográficos
Main Authors: Morey Kinney, Shannon R., Zhang, Wa, Pascual, Marien, Greally, John M., Gillard, Bryan M., Karasik, Ellen, Foster, Barbara A., Karpf, Adam R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789312/
https://ncbi.nlm.nih.gov/pubmed/19934341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0010
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