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Opposing Roles of Dnmt1 in Early- and Late-Stage Murine Prostate Cancer
Previous studies have shown that tumor progression in the transgenic adenocarcinoma of mouse prostate (TRAMP) model is characterized by global DNA hypomethylation initiated during early-stage disease and locus-specific DNA hypermethylation occurring predominantly in late-stage disease. Here, we util...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937561/ https://ncbi.nlm.nih.gov/pubmed/20584988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00235-10 |
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