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Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons

It is well known that Rett Syndrome, a severe postnatal childhood neurological disorder is mostly caused by mutations in the MECP2 gene. However, how deficiencies in MeCP2 contribute to the neurological dysfunction of Rett Syndrome is not clear. We aimed to resolve the role of MeCP2 epigenetic regul...

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Библиографические подробности
Главные авторы: Smrt, Richard D, Eaves-Egenes, Julialea, Barkho, Basam Z., Santistevan, Nicholas J., Zhao, Chunmei, Aimone, James B., Gage, Fred H., Zhao, Xinyu
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789309/
https://ncbi.nlm.nih.gov/pubmed/17532643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.04.005
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