Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons

It is well known that Rett Syndrome, a severe postnatal childhood neurological disorder is mostly caused by mutations in the MECP2 gene. However, how deficiencies in MeCP2 contribute to the neurological dysfunction of Rett Syndrome is not clear. We aimed to resolve the role of MeCP2 epigenetic regul...

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Bibliografiske detaljer
Main Authors: Smrt, Richard D, Eaves-Egenes, Julialea, Barkho, Basam Z., Santistevan, Nicholas J., Zhao, Chunmei, Aimone, James B., Gage, Fred H., Zhao, Xinyu
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789309/
https://ncbi.nlm.nih.gov/pubmed/17532643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.04.005
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