Epigenetic Regulation of the Stem Cell Mitogen Fgf-2 by Mbd1 in Adult Neural Stem/Progenitor Cells

Whether and how mechanisms intrinsic to stem cells modulate their proliferation and differentiation are two central questions in stem cell biology. Although exogenous basic fibroblast growth factor 2 (FGF-2/Fgf-2) is commonly used to expand adult neural stem/progenitor cells (NSPCs) in vitro, we do...

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Bibliografiske detaljer
Main Authors: Li, Xuekun, Barkho, Basam Z., Luo, Yuping, Smrt, Richard D., Santistevan, Nicholas J., Liu, Changmei, Kuwabara, Tomoko, Gage, Fred H., Zhao, Xinyu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Molecular Basis of Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562066/
https://ncbi.nlm.nih.gov/pubmed/18689796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804899200
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