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Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation
Methyl-CpG binding protein 1 (MBD1) regulates gene expression via a DNA methylation-mediated epigenetic mechanism. We have previously demonstrated that MBD1 deficiency impairs adult neural stem/progenitor cell (aNSC) differentiation and neurogenesis, but the underlying mechanism was unclear. Here we...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867837/ https://ncbi.nlm.nih.gov/pubmed/20452318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.02.017 |
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