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Increased ADAM17 mRNA Expression and Activity is Associated with Atherosclerosis Resistance in LDL-Receptor Deficient Mice

BACKGROUND: We have previously identified an atherosclerosis quantitative trait locus (QTL) on mouse chromosome (Chr) 12 in an F2-intercross of atherosclerosis-resistant FVB and atherosclerosis-susceptible C57BL/6 (B6) mice on the LDL-receptor deficient background. The aim of the present study was t...

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Detalhes bibliográficos
Main Authors: Holdt, Lesca M., Thiery, Joachim, Breslow, Jan L., Teupser, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789234/
https://ncbi.nlm.nih.gov/pubmed/18356551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.165654
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