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Structure of the Taz2 domain of p300: insights into ligand binding

CBP and its paralog p300 are histone acetyl transferases that regulate gene expression by interacting with multiple transcription factors via specialized domains. The structure of a segment of human p300 protein (residues 1723–1836) corresponding to the extended zinc-binding Taz2 domain has been inv...

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Autors principals: Miller, Maria, Dauter, Zbigniew, Cherry, Scott, Tropea, Joseph E., Wlodawer, Alexander
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789004/
https://ncbi.nlm.nih.gov/pubmed/19966416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909040153
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