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Stimulation of Tissue Plasminogen Activator Production by Retinoic Acid: Synergistic Effect on Protein Kinase C-Mediated Activation

Trans retinoic acid (t-RA) stimulated the production of tissue plasminogen activator (tPA) in HeLa-S(3) and human umbilical vein endothelial cells (huvecs) in a dose-dependent manner with maximal release (four to five times control) at 40 nmol/L and 40 µmol/L, respectively. In endothelial cells, the...

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Detalhes bibliográficos
Main Authors: Medh, Rheem D., Santell, Lydia, Levin, Eugene G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788990/
https://ncbi.nlm.nih.gov/pubmed/1323347
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