Endothelium-Derived Hyperpolarizing Factor Mediates Bradykinin Stimulated Tissue Plasminogen Activator Release In Humans

AIMS: Bradykinin stimulates tissue plasminogen activator (t-PA) release from human endothelium. Although bradykinin stimulates both nitric oxide and endothelium-derived hyperpolarizing factor (EDHF) release, the role of EDHF in t-PA release remains unexplored. This study sought to determine the mech...

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Hauptverfasser: Rahman, Ayaz M., Murrow, Jonathan R., Ozkor, Muhiddin A., Kavtaradze, Nino, Lin, Ji, De Staercke, Christine, Hooper, W. Craig, Manatunga, Amita, Hayek, Salim, Quyyumi, Arshed A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149839/
https://ncbi.nlm.nih.gov/pubmed/24925526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000362666
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